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Dermatology (Basel) · Jan 2015
Positive reactions to nickel on a patch test do not predict clinical outcome of nickel alloy-based atrial septal defect occluder implantation.
- Hee Joo Kim, Jung U Shin, Jungsoo Lee, Hemin Lee, Shan Jin, Seo Hyeong Kim, Ji Yeon Noh, and Kwang Hoon Lee.
- Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
- Dermatology (Basel). 2015 Jan 1; 230 (2): 184-8.
BackgroundPatch testing is thought to be necessary prior to metal device implantation to rule out metal allergy-related complications; however, there are controversies over the effects of nickel allergy on the outcome of nickel alloy-based device implantation.ObjectiveThis study aimed to evaluate the adverse events in a Korean population of nickel allergy patients who underwent atrial septal defect (ASD) closure with a nickel-titanium alloy-based device.MethodsWe retrospectively reviewed the medical records of patients who underwent ASD closure with a nitinol device.ResultsAmong 38 patients who had ASD closure, 4 of 5 nickel-allergic patients and 10 of the 33 non-nickel-allergic patients had post-closure complications. All patients fared well, without device failure culminating in device removal.ConclusionIn this study, positive reactions to nickel in a patch test were not associated with adverse early or late outcomes following ASD closure with a nickel alloy-based device.© 2015 S. Karger AG, Basel.
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