• Middle East J Anaesthesiol · Jun 2012

    Randomized Controlled Trial

    Recovery profile and emergence delirium following sevoflurane and isoflurane anesthesia in children posted for cleft lip surgery.

    • Parul Jindal, Gurjeet Khurana, Deepak Oberoi, and Jagdish Prasad Sharma.
    • Department of Anaesthesiology, Intensive Care and Pain Management, Himalayan Institute of Medical Sciences, Swami Rama Nagar, Dehradun. parulpjindal@yahoo.co.in
    • Middle East J Anaesthesiol. 2012 Jun 1;21(5):679-84.

    UnlabelledThis prospective, randomized, double control study was carried out in 84 children aged 2-24 months posted for elective cleft lip surgery.MethodsPatients were randomally divided into 2 groups of 42 patients each. In Group A patients were induced and maintained on sevoflurane while in Group B patients were induced with sevoflurane and maintained on isoflurane. Standardized anesthesia technique was used. Recovery milestones and post operative complications were recorded.ResultsIncidence of emergence delirium in sevoflurane group was 11.9% while in isoflurane group is 2.38%. The overall incidence of emergence delirium in the study was 7.14%. There was no significant difference (p > 0.05) in the incidence of emergence delirium between the two groups. There was no effect of duration of exposure of sevoflurane and time taken for achievement of recovery milestones while we observed a positive correlation with isoflurane. In sevoflurane the recovery endpoint first reached was limb movement > spontaneous respiration > spontaneous eye opening. In isoflurane group the recovery end point first reached was spontaneous respiration > limb movement = spontaneous eye opening.ConclusionOur study confirms that the recovery profile of sevoflurane in children less the two years is superior compared to isoflurane.

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