• Chest · Jan 2022

    Case Reports

    A 67-Year-Old Male Patient With COVID-19 With Worsening Respiratory Function and Acute Kidney Failure.

    • Max Melchers, Barbara Festen, Bianca M den Dekker, Eline R M Mooren, Annelien L van Binsbergen, van BreeSjoerd H WSHWDepartment of Intensive Care Medicine, Hospital Gelderse Vallei, Ede, The Netherlands., Moniek Heusinkveld, Roel Schellaars, Jochem B Buil, Paul E Verweij, and van ZantenArthur R HARHDepartment of Intensive Care Medicine, Hospital Gelderse Vallei, Ede, The Netherlands; Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, The Netherlands. Electronic address: zantena@zgv.nl..
    • Department of Intensive Care Medicine, Hospital Gelderse Vallei, Ede, The Netherlands.
    • Chest. 2022 Jan 1; 161 (1): e5e11e5-e11.

    AbstractA 67-year-old obese man (BMI 38.0) with type 2 diabetes mellitus (DM), chronic atrial fibrillation, and chronic lymphocytic leukemia stage II, stable for 8 years after chemotherapy, and a history of smoking presented to the ED with progressive dyspnea and fever due to SARS-CoV-2 infection. He was admitted to a general ward and treated with dexamethasone (6 mg IV once daily) and oxygen. On day 3 of hospital admission, he became progressively hypoxemic and was admitted to the ICU for invasive mechanical ventilation. Dexamethasone treatment was continued, and a single dose of tocilizumab (800 mg) was administered. On day 9 of ICU admission, voriconazole treatment was initiated after tracheal white plaques at bronchoscopy, suggestive of invasive Aspergillus tracheobronchitis, were noticed. However, his medical situation dramatically deteriorated.Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved.

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