• Journal of critical care · Jun 2022

    Randomized Controlled Trial Multicenter Study

    Steps to recovery: Body weight-supported treadmill training for critically ill patients: A randomized controlled trial.

    • Robin C H Kwakman, Eric L Voorn, Janneke Horn, Frans Nollet, EngelbertRaoul H HRHHAmsterdam UMC, University of Amsterdam, Department of Rehabilitation Medicine, Amsterdam Movement Sciences, Meibergdreef 9, Amsterdam, Netherlands; Faculty of Health, Center of Expertise Urban Vitality, Amsterdam University of Applied, Juultje Sommers, and Marike van der Schaaf.
    • Amsterdam UMC, University of Amsterdam, Department of Rehabilitation Medicine, Amsterdam Movement Sciences, Meibergdreef 9, Amsterdam, Netherlands; Faculty of Health, Center of Expertise Urban Vitality, Amsterdam University of Applied Sciences, Amsterdam, the Netherlands; Education of Physiotherapy, University of Applied Sciences Amsterdam, Amsterdam, the Netherlands. Electronic address: r.c.h.kwakman@hva.nl.
    • J Crit Care. 2022 Jun 1; 69: 154000.

    PurposeEarly mobilization of critically ill patients improves functional recovery, but is often hampered by tubes, drains, monitoring devices and muscular weakness. A mobile treadmill with bodyweight support facilitates early mobilization and may shorten recovery time to independent ambulation as compared to usual care physiotherapy alone.Materials And MethodsSingle center RCT, comparing daily bodyweight supported treadmill training (BWSTT) with usual care physiotherapy, in patients who had been or were mechanically ventilated (≥48 h) with ≥MRC grade 2 quadriceps muscle strength. BWSTT consisted of daily treadmill training in addition to usual care physiotherapy (PT). Primary outcome was time to independent ambulation measured in days, using the Functional Ambulation Categories (FAC-score: 3). Secondary outcomes included hospital length of stay and serious adverse events.ResultsThe median (IQR) time to independent ambulation was 6 (3 to 9) days in the BWSTT group (n = 19) compared to 11 (7 to 23) days in the usual care group (n = 21, p = 0.063). Hospital length of stay was significantly different in favour of the BWSTT group (p = 0.037). No serious adverse events occurred.InterpretationBWSTT seems a promising intervention to enhance recovery of ambulation and shorten hospital length of stay of ICU patients, justifying a sufficiently powered multicenter RCT.Trial Registration NumberDutch Trial Register ID: NTR6943.Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.

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