• Omer Ozkan, Ozlenen Ozkan, Nasuh Utku Dogan, Mustafa Bahceci, Inane Mendilcioglu, Kubra Boynukalin, Hakan Ongun, Abdul Mecit Kantarci, Muhittin Yaprak, Melike Cengiz, Necmiye Hadimioglu, Yusuf Taner Kafadar, and Kiymet Celik.
• Akdeniz University Faculty of Medicine Department of Plastic Surgery, Antalya, Turkey.
• Ann. Surg. 2022 May 1; 275 (5): 825-832.

ObjectiveTo describe surgical procedures, previous failed pregnancies, methods for overcoming pregnancy failure and, most importantly, birth of a healthy infant, in a uterus transplantation from a deceased donor.BackgroundMajority of uterus transplants have involved live donors, but several advantages make deceased donor transplantation a practicable option, principally by eliminating surgical risks to the live donor.MethodsUterus transplantation from a deceased donor was performed in September 2011 in Turkey. After 5 miscarriages, perfusion computed tomography revealed an obstructed blood-outflow. To overcome this blood flow obstruction, a saphenous vein graft was anastomosed between utero-ovarian and left ovarian vein with laparotomy. Follow-up computed tomography confirmed resolution of venous congestion and a decrease in uterine volume.ResultsFollowing vascular augmentation surgery, fetal cardiac activity were observed 28 days after the first embryo transfer attempt. Preterm premature rupture of the membranes was diagnosed at 19 weeks' gestation. Cesarean section was planned at 28 weeks' gestation due to intrauterine growth restriction and suspected preeclampsia. A healthy 760 g male baby was delivered. The baby was discharged from the neonatal intensive care unit 79 days after delivery in good condition weighing 2475 g.ConclusionsDeceased donor uterus transplantation is a reasonable approach for treating uterine factor-related infertility. In case of recurrent miscarriages, regional vascular augmentation by arterial or venous supercharging may be required to overcome regional misperfused regions determined by imaging studies.Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

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