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Minerva anestesiologica · Sep 2022
Multidrug-resistant infections in solid organ transplant recipients: a focus on risk factors, prevention and treatment strategies.
- Dmitri Bezinover, Gianni Biancofiore, Marco Falcone, Costantine Karvellas, Shaid Husain, and Fuat H Saner.
- Department of Anesthesiology and Perioperative Medicine, Penn State Hershey Medical Center, Penn State College of Medicine, Hershey, PA, USA.
- Minerva Anestesiol. 2022 Sep 1; 88 (9): 735-747.
AbstractSolid organ transplantation is the best therapeutic option for patients with end-stage organ disease and, according to the data from international registries, there has been a steady increase in numbers and results. However, post‑transplant infections remain a fearsome complication with, in the last decade, an increasing incidence of episodes due to antibiotic‑resistant bacteria and opportunistic agents. In this paper, we summarized the most relevant and updated knowledge concerning infections from multidrug‑resistant germs in solid organ transplant recipients, focusing on risk factors, treatment and prevention strategies, and antimicrobial pharmacokinetics relevant to this population of patients.
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