• Revista médica de Chile · Aug 2021

    Review

    [Measurement of exhaled nitric oxide fraction in lung diseases].

    • Luz Miranda and Julia Guerrero.
    • Laboratorio de Inmunomodulación Neuroendocrina, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
    • Rev Med Chil. 2021 Aug 1; 149 (8): 1173-1181.

    AbstractExhaled Nitric Oxide fraction measurement is a new method for the evaluation of respiratory diseases. It has good correlation with airway inflammation and decreases with the administration of corticosteroids. It is useful as a complement for the diagnosis of asthma, Chronic Obstructive Pulmonary Disease, Cystic Fibrosis and Primary Ciliary Dyskinesia among other respiratory diseases that generate inflammation in the airway. Its assessment is easy, non-invasive, and safe, and the result is obtained immediately. It can be used routinely to evaluate the response and adherence to treatments. This article reviews the biology of Nitric Oxide, and the measurement, interpretation, and main clinical uses of Exhaled Nitric Oxide Fraction.

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