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Internal medicine journal · Dec 2014
ReviewConsensus guidelines for diagnosis, prophylaxis and management of Pneumocystis jirovecii pneumonia in patients with haematological and solid malignancies, 2014.
- L Cooley, C Dendle, J Wolf, B W Teh, S C Chen, C Boutlis, and K A Thursky.
- Department of Microbiology and Infectious Diseases, Royal Hobart Hospital, Hobart, Tasmania.
- Intern Med J. 2014 Dec 1; 44 (12b): 1350-63.
AbstractPneumocystis jirovecii infection (PJP) is a common cause of pneumonia in patients with cancer-related immunosuppression. There are well-defined patients who are at risk of PJP due to the status of their underlying malignancy, treatment-related immunosuppression and/or concomitant use of corticosteroids. Prophylaxis is highly effective and should be given to all patients at moderate to high risk of PJP. Trimethoprim-sulfamethoxazole is the drug of choice for prophylaxis and treatment, although several alternative agents are available. © 2014 The Authors; Internal Medicine Journal © 2014 Royal Australasian College of Physicians.
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