• Medicine · Mar 2022

    Efficacy of Geumguesingi-hwan (jinkuishenqi-wan, kinkijinki-gan) in decreasing blood glucose levels in patients with uncomplicated type 2 diabetes: A protocol for systematic review and meta-analysis.

    • Hyun-Jin Choi, Ji-Soo Baek, Cheon-Hoo Jeon, Seon-Mi Shin, and Chung-Sik Cho.
    • College of Korean Medicine, Daejeon University, Daejeon, Republic of Korea.
    • Medicine (Baltimore). 2022 Mar 25; 101 (12): e29079.

    BackgroundThe purpose of a systematic review and meta-analysis is to verify the clinical efficacy and safety of Geumguesingihwan for patients with uncomplicated type 2 diabetes.MethodsThe systematic review and meta-analysis will be performed following the guidelines of the National Evidence-based Healthcare Collaborating Agency. We will conduct a systematic search of randomized controlled trials in 8 electronic databases until August 31, 2021.ResultsThis study will provide evidence regarding the clinical efficacy of Geumguesingi-hwan from the following 3 perspectives: improving blood glucose level, insulin resistance, and β-cell function. Additionally, we will examine the safety of Geumguesingi-hwan by evaluating the adverse effects.ConclusionsThis study will verify the antidiabetic efficacy and safety of Geumguesingi-hwan in patients with uncomplicated type 2 diabetes.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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