• Internal medicine journal · Feb 2023

    Idiopathic factor V inhibitor in a patient starting haemodialysis.

    • Luke J Sutherland, Sarah Tan, and Merit Hanna.
    • Department of Medicine, North Shore Hospital, Auckland, New Zealand.
    • Intern Med J. 2023 Feb 1; 53 (2): 289292289-292.

    AbstractA 74-year-old Pacific Island man with end-stage renal failure planning to start haemodialysis presented with persistent bleeding after tunnelled dialysis catheter insertion. The laboratory findings revealed a prolonged activated partial thromboplastin time of 118 s, prothrombin ratio of 4.2, factor V activity of <2% and a factor V inhibitor of 40 Bethesda Units. No clear underlying aetiology was identified. The bleeding settled with conservative measures and the factor V inhibitor was successfully treated with oral cyclophosphamide for 6 weeks.© 2022 Royal Australasian College of Physicians.

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