• Fuhong Zhang, Ji Chen, Xunwen Lei, Xiaowan Chen, and Xiaobing Zhang.
• Department of Otolaryngology Head and Neck Surgery, First Hospital of Lanzhou University.
• Medicine (Baltimore). 2019 Jun 1; 98 (24): e16007e16007.

BackgroundChronic sinusitis (CRS) is a high incidence disease and seriously affects the patients' quality of life, causes tremendous economic burden as well. Endoscopic sinus surgery (ESS) is one of the most common therapies for chronic sinusitis. While whether there is a need for nasal packing and which is the best one is still unclear.Method And AnalysisA systematic search will be performed using PubMed, EMBASE.com, the Cochrane Central Register of Controlled Trials, Chinese Biomedical Literature Database, China National Knowledge Infrastructure and Wanfang database to include randomized controlled trials (RCTs), comparing the efficacy and comfort in patients with nasal packings after ESS who is diagnosed as CRS. The risk of bias of the included RCTs will be assessed by the Cochrane Handbook version 5.1.0. A Bayesian network meta-analysis will be conducted using R-3.3.2 software.ResultsThis study is ongoing and the results will be published in a peer-reviewed journal.ConclusionThe results of this study will be sent to clinicians and healthcare providers in the National Health Service, which is expected to help clinicians make more informed choices on nasal packings.Ethics And DisseminationEthical approval is not applicable since this study is a network meta-analysis based on published trials.Protocol Registration NumberCRD42019119233.

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