• Pablo Antonio Kuri-Morales, Guadalupe Díaz Del Castillo-Flores, Andrés Castañeda-Prado, and Salma Rosario Pacheco-Montes.
• Universidad Nacional Autónoma de México, Facultad de Medicina, Ciudad de México. México.
• Gac Med Mex. 2019 Jan 1; 155 (5): 457-463.

IntroductionInfluenza epidemics are of higher risk at the extremes of life and in people with comorbidities. Effective -vaccination prevents the occurrence of serious cases and decreases mortality.ObjectiveTo describe deaths from influenza with a history of timely vaccination, from the 2010 to the 2018 season in Mexico.MethodCross-sectional, descriptive study where the Influenza Epidemiological Surveillance System database was used.ResultsFrom 2010 to 2018, 65 vaccinated individuals died from influenza, from which 55% of cases (n = 36) were due to type A (H1N1), 51% (n = 33) were females, median age was 57 years, 21 % (n = 14) did not meet the operational definition of influenza-like illness or severe acute respiratory infection, 83% (n = 54) had at least one comorbidity, with the most common being diabetes mellitus and hypertension (32% each); 55% (n = 36) of deaths received antiviral treatment and only 8% (n = 5) had no comorbidities and received treatment with oseltamivir.ConclusionsDeaths from influenza with timely vaccination represent a very low percentage of the totality. Vaccination against influenza has been a specific prevention strategy that decreases disease burden.Copyright: © 2019 Permanyer.

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