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Review Case Reports
CD3- and CD4-positive plasmablastic lymphoma: a literature review of Japanese plasmablastic lymphoma cases.
- Yuhko Suzuki, Tsutomu Yoshida, Naoya Nakamura, Hirotoshi Kamata, Shouko Kotani, Manabu Ohsaka, Sabine Kajita, Koji Miyazaki, Shinichi Ohtani, Meijin Nakayama, Ryouichi Horie, Kazushige Hayakawa, Nozomi Niitsu, and Masaaki Higashihara.
- Department of Hematology, Kitasato University School of Medicine, Sagamihara, Japan. ysuzuki-hki@umin.ac.jp
- Intern. Med. 2010 Jan 1; 49 (16): 180118051801-5.
AbstractPlasmablastic lymphoma (PBL) is a very rare and recently-described subtype of diffuse large B-cell lymphoma. A maxillary tumor in an 84-year-old HIV-negative Japanese-man was referred. The biopsied specimen showed a diffuse proliferation of mature plasma cells, expressing CD3 (+), CD4 (+), CD20 (-), CD138 (+) and EBER (+) by immunohistochemistry. He was diagnosed as a plasmablastic lymphoma; radiation therapy (RT) was started, but the response to the RT was only a partial response. To our knowledge, this is the first report of a patient with PBL expressing CD3 and CD4.
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