• Lianlian Lei, Quincy M Samus, Kali S Thomas, and Donovan T Maust.
• Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA. leilian@med.umich.edu.
• J Gen Intern Med. 2023 Feb 1; 38 (2): 294301294-301.

BackgroundAssisted-living (AL) settings are an important residential care option for old and disabled Americans, but there are no national data characterizing medication use in AL.ObjectiveTo investigate medication costs and use of older adults living in the AL settings compared to those in the community, independent living, and nursing home settings.Design2015 National Health and Aging Trends Study; nationally representative cross-sectional study.PaticipantsRespondents ≥ 65 years with Medicare Part D prescription drug coverage (n = 5980, representing 32.34 million older adults).MeasuresTotal Part D medication costs; number of 30-day prescription fills; binary indicators for overall polypharmacy (≥ 5 and ≥ 10 concurrent medications), prescription fills of opioid and psychotropic medications including antipsychotics, benzodiazepines, gabapentinoids, antidepressants, and central nervous system-active (CNS-active) polypharmacy.ResultsAdjusting for demographics, the annual medication costs among AL residents, at $3890, were twice as high as those of their community-dwelling counterparts ($1932; p < .01). All medication outcomes except opioids were higher for older adults in AL compared to community settings. While the adjusted number of 30-day prescription fills among AL residents was slightly lower than that of nursing home residents (89.5 vs. 106.2; p < .05), AL residents experienced equivalent rates of overall polypharmacy ≥ 10 medications (30.2% vs. 23.5%), antipsychotics (30.8% vs. 27.8%), benzodiazepines (30.7% vs. 32.6%), gabapentinoids (21.2% vs. 16.1%), and CNS-active polypharmacy (26.0% vs. 36.9%; p > .05 for all). Patterns of use across settings were consistent when limited to older adults with dementia.ConclusionsOlder Americans in AL experience a prescription medication burden similar to those in nursing homes. AL settings have an important opportunity to ensure their medication-related clinical services and supports match the needs of their residents.© 2022. The Author(s) under exclusive licence to Society of General Internal Medicine.

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