• Min Cheng, Xiu-E Zhou, Yu-Chen Xu, and Hong-Mei Dou.
• Digestive Endoscopy Center, Taizhou People's Hospital, Jiangsu, China.
• Medicine (Baltimore). 2022 May 13; 101 (19): e29157e29157.

BackgroundFunctional dyspepsia and digestive disorders are common, debilitating and costly. Little information is available about the role of stress management in terms of cognitive-behavioral treatment of dyspepsia. We performed a protocol for systematic review and meta-analysis to evaluate the effectiveness of cognitive behavior stress management for the treatment of functional dyspepsia.MethodsA comprehensive search of several databases from 1966 to March 2022 will be conducted. The databases include Ovid Medline In-Process & Other Non-Indexed Citations, Ovid MEDLINE, Ovid EMBASE, Ovid PsycINFO, Ovid Cochrane Central Register of Controlled Trials, Ovid Cochrane Database of Systematic Reviews, and Scopus. The primary outcome for this study was the rate of successful treatment (presence of no more than mild pain or discomfort after treatment). The secondary outcomes were improvement of dyspepsia at short-term (<1 year) and long-term (≥1 year) follow up, improvement in quality of life, and development of treatment-related adverse events. The risk of bias in each included study will be assessed utilizing the Cochrane Collaboration's risk of bias tool. The Review Manager 5.3 (Cochrane Collaboration, Oxford, UK) will be used to analyze the data.ResultsWe will synthesize the current studies to evaluate the effectiveness and safety of cognitive behavior stress management on functional dyspepsia.ConclusionThe result of this review will provide more reliable references to help clinicians make decisions when dealing with functional dyspepsia.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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