• Aisikeer Tulahong, Tuerhongjiang Tuxun, Gang Yao, Xiapukati Fulati, Shadike Apaer, Nuerzhatijiang Anweier, Jing Wu, Amina Aierken, Jin-Ming Zhao, Lei Bai, and Tao Li.
• 2 Oncology Department, Center of Oncology, 1 Affiliated Hospital of Xinjiang Medical University, Urumqi.
• Medicine (Baltimore). 2022 Jun 3; 101 (22): e29326e29326.

ObjectivesLeiomyosarcoma of inferior vena cava (IVC) is a rare clinical entity with severe vascular involvement. Surgical management of leiomyosarcoma is still challenging.MethodsThis a retrospective study of consecutive patients referred to our hospital from January 2017 to June 2019. Depending on the anatomical site of affected IVC, leiomyosarcomas were categorized into zone I-II. The clinical data including baseline information, surgical parameters, peri-operative management, short- and mid-term outcomes were observed.ResultsFour patients with leiomyosarcoma of zone I-III underwent radical resection without intraoperative mortality. Prosthetic grafts were interpositioned in all patients to instruct vena cava. Renal vein reconstruction was perfumed in two patients due to involvement to renal veins. Median blood loss was 450 mL (200-600 mL), median operative time was 215 minutes (150-240 minutes). No Clavien-Dindo IIIa or higher complication was observed. No organ dysfunction and recurrence were observed with median follow-up of 25.5 months.ConclusionsCurative resection of zone I-II leiomyosarcoma is associated with longer survival in selected cases, en-bloc resection with complex vascular reconstruction could be considered.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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