• J Clin Anesth · Aug 2007

    Case Reports

    Dexmedetomidine as sole sedative for awake intubation in management of the critical airway.

    • Basem Abdelmalak, Laila Makary, Jeremy Hoban, and D John Doyle.
    • Department of General Anesthesiology, Cleveland Clinic, Cleveland, OH 44195, USA. abdelmb@ccf.org
    • J Clin Anesth. 2007 Aug 1;19(5):370-3.

    AbstractWe report a series of successful awake fiberoptic intubations in patients with critical (unstable, difficult) airways using the alpha(2)-agonist, dexmedetomidine. Dexmedetomidine has several desirable pharmacologic properties, including sedation, anxiolysis, hypnosis, analgesia, amnesia, antisialagogue effects, and a unique respiratory-sparing effect. Dexmedetomidine appears to be a useful agent for sedation during awake fiberoptic intubation in difficult airway patients.

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