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Case Reports
Multisystem Inflammatory Syndrome in Adults Accompanied with Kikuchi-Fujimoto Disease: A Case Report.
- Eriko Kashihara, Kosuke Doi, and Kohei Fujita.
- Department of Infectious Diseases, National Hospital Organization Kyoto Medical Center, Japan.
- Intern. Med. 2022 Aug 15; 61 (16): 2527-2532.
AbstractWe herein report a case of multisystem inflammatory syndrome in adults (MIS-A) complicated with Kikuchi-Fujimoto disease (KFD). A previously healthy 41-year-old man presented with painful swelling of the cervical lymph nodes, fever, diarrhea, conjunctivitis, edema, and hypotension one month after the onset of asymptomatic coronavirus disease 2019. Laboratory investigations revealed an elevation of CRP, and echocardiography indicated diastolic dysfunction. We diagnosed the patient to have MIS-A. Histopathology of the lymph nodes showed necrotizing lymphadenitis. After the initiation of hydrocortisone and diuretics, his symptoms resolved immediately. This case suggested that post-viral immune dysregulation in MIS-A could play a role in the etiology of KFD.
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