• Taylor E Dlesk and Karen Larimer.
• DePaul University School of Nursing, Chicago, Illinois. Electronic address: taylor.dlesk@gmail.com.
• Pain Manag Nurs. 2023 Feb 1; 24 (1): 102110102-110.

ObjectivesThe objective of this literature review was to evaluate multimodal therapies and interventions that help prevent progression and manage pain in children with OI.DesignA systematic review of literature utilizing PRISMA guidelines.Data SourcesThe Cumulative Index to Nursing and Allied Health Literature (CINAHL) Complete, PubMed, PsycINFO, UpToDate, and ProQuest Nursing & Allied Health Source.Review/Analysis MethodsExisting literature on pain management in pediatric patients diagnosed with OI was reviewed and appraised. Fifteen studies met the criteria for review.ResultsResults indicated that therapies addressing pain management are most effective when they use a multimodal approach that promotes bone strength, psychological support, reduces the risk of fractures, increases bone stability, and maintains physiological function. Four multimodal treatments for pain management in children with OI were identified including bisphosphonate therapy, surgical intervention, physical therapy, and psychosocial support.ConclusionsDeveloping a finite understanding of the utilization of multimodal therapies to manage and treat pain can assist in engineering treatments that improve the quality of life for children diagnosed with OI.Copyright © 2022 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved.

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