• Zheng Guo, Yongjun Li, Yiming Hou, Youpeng Wang, Yuan Liang, Xiuying Si, Guangxia Pan, Yijie Wang, and Qihui Hu.
• Heilongjiang University of Chinese Medicine, Harbin, China.
• Medicine (Baltimore). 2022 Nov 25; 101 (47): e31923e31923.

BackgroundTo conduct a systematic review of the efficacy of Chinese herbal bath therapy on children with Atopic dermatitis.MethodsWe searched Chinese databases (CNKI, VIP, and Wanfang) and English databases (PubMed, Embase, Web of science, Cochrane library) for studies from the establishment of the database to September 2022. The included literature was randomized control studies investigating the treatment of Atopic dermatitis in children by Chinese herbal bath therapy. The outcomes included the cure rate, scoring atopic dermatitis (SCORAD) index, adverse reactions and recurrence rate. RevMan 5.4 was used to analyze the extracted data.ResultsA total of 8 related studies were included containing 854 cases. The meta-analysis showed that Chinese herbal bath therapy group was superior to control group in terms of cure rate, SCORAD index, adverse reactions and recurrence rate in children with Atopic dermatitis [RR = 1.11, 95%(1.02, 1.21), P = .01; SMD = -0.77, 95%(-0.99, -0.55), P < .00001; RR = 0.44, 95%CI(0.28,0.67), P = .0002; RR = 0.25, 95%CI(0.10, 0.59), P = .0002].ConclusionThe present study shows that Chinese herbal bath therapy is an effective treatment for children with Atopic dermatitis in China.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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