• Chest · Jul 1991

    Case Reports

    Coronary vasospasm secondary to labetalol in a patient with aortic dissection.

    • M A Sandler, L E Jacobs, and M N Kotler.
    • Division of Cardiovascular Disease, Albert Einstein Medical Center, Philadelphia 19141.
    • Chest. 1991 Jul 1; 100 (1): 261262261-2.

    AbstractA 66-year-old hypertensive woman presented with epigastric and scapular pain on the basis of type 3 aortic dissection. Appropriate therapy with a combined alpha-adrenergic and beta-adrenergic antagonist agent prevented further ongoing dissection and amelioration of symptoms. On day 5, an episode of coronary vasospasm occurred presumably due to beta-blockade with unopposed alpha-adrenergic activity.

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