• Emre Leventoğlu, AtikelYeşim ÖzdemirYÖDepartment of Pediatric Nephrology, Eskişehir City Training and Research Hospital, Eskişehir, Turkey., Hülya Nalçacıoğlu, İsmail Dursun, Hasan Dursun, Zeynep Nagehan Yürük Yıldırım, Nurdan Yıldız, Gülşah Kaya Aksoy, Mehmet Taşdemir, Mehtap Çelakıl, Beltinge Demircioğlu Kılıç, Şenay Zırhlı Selçuk, Nur Canpolat, Evrim Kargın Çakıcı, Sare Gülfem Özlü, Sebahat Tülpar, Selçuk Yüksel, Bahriye Atmış, DövenSerra SürmeliSSDepartment of Pediatric Nephrology, Faculty of Medicine, Mersin University, Mersin, Turkey., Sevgin Taner, Pelin Ertan, Aslı Kavaz Tufan, Meral Torun Bayram, Mukaddes Kalyoncu, Kaan Savaş Gülleroğlu, Süleyman Caner Kabasakal, DemirBelde KasapBKDepartments of Pediatric Nephrology and Rheumatology, Faculty of Medicine, İzmir Katip Çelebi University, İzmir, Turkey., Rumeysa Yasemin Çiçek Gülşan, Ilmay Bilge, Osman Dönmez, Aslıhan Kara, Önder Yavaşcan, Gül Özçelik, YıldırımDeniz GezginDGDepartments of Pediatric Nephrology and Rheumatology, Faculty of Medicine, Gazi University, Ankara, Turkey., Muhammet Akif Güler, Ferah Sönmez, Muammer Hakan Poyrazoğlu, Sema Akman, Rezan Topaloğlu, Harika Alpay, and Sevcan Azime Bakkaloğlu Ezgü.
• Departments of Pediatric Nephrology and Rheumatology, Faculty of Medicine, Gazi University, Ankara, Turkey.
• Turk J Med Sci. 2022 Dec 1; 52 (6): 176217701762-1770.

BackgroundThere is limited data on COVID-19 disease in children with kidney disease. We aimed to investigate the characteristics and prognosis of COVID-19 in pediatric nephrology patients in Turkey.MethodsThis was a national, multicenter, retrospective cohort study based on an online survey evaluating the data between 11th March 2020 and 11th March 2021 as an initial step of a detailed pediatric nephrology COVID-19 registry.ResultsTwo hundred and three patients (89 girls and 114 boys) were diagnosed with COVID-19. One-third of these patients (36.9%) were between 10-15 years old. Half of the patients were on kidney replacement therapy: kidney transplant (KTx) recipients (n = 56, 27.5%), patients receiving chronic hemodialysis (n = 33, 16.3%) and those on peritoneal dialysis (PD) (n = 18, 8.9%). Fifty-four (26.6%) children were asymptomatic. Eighty-two (40.3%) patients were hospitalized and 23 (28%) needed intensive care unit admission. Fifty-five percent of the patients were not treated, while the remaining was given favipiravir (20.7%), steroid (16.3%), and hydroxychloroquine (11.3%). Acute kidney injury developed in 19.5% of hospitalized patients. Five (2.4%) had MIS-C. Eighty-three percent of the patients were discharged without any apparent sequelae, while 7 (3.4%) died. One hundred and eight health care staff were infected during the study period.DiscussionCOVID-19 was most commonly seen in patients who underwent KTx and received HD. The combined immunosuppressive therapy and frequent exposure to the hospital setting may increase these patients' susceptibility. Staff infections before vaccination era were alarming, various precautions should be taken for infection control, particularly optimal vaccination coverage.

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