• Res Dev Disabil · Mar 2012

    Comparative Study

    Salivary alpha amylase and cortisol levels in children with global developmental delay and their relation with the expectation of dental care and behavior during the intervention.

    • Márcio José Possari dos Santos, Daniel Galera Bernabé, Ana Cláudia de Melo Stevanato Nakamune, Silvia Helena Venturoli Perri, Sandra Maria Herondina Coelho Ávila de Aguiar, and Sandra Helena Penha de Oliveira.
    • Center for Dental Care of Persons with Disabilities - CAOE, School of Dentistry of Araçatuba, UNESP - Univ Estadual Paulista, Araçatuba, São Paulo, Brazil. marciokada@hotmail.com
    • Res Dev Disabil. 2012 Mar 1;33(2):499-505.

    AbstractThe purpose of this study was to analyze the alpha-amylase (sAA) and cortisol levels in children with Global developmental delay (GDD) before and after dental treatment and its association with the children's behavior during treatment. The morning salivary cortisol levels and activity of sAA of 33 children with GDD were evaluated before and after dental treatment and were compared to 19 healthy children. The behavior of children with GDD during dental care was assessed by the Frankl scale. Children with GDD showed lower levels of sAA activity than healthy children, but this result was not significant. The salivary cortisol levels were similar between GDD and healthy children. GDD children showed increased levels of sAA (but not cortisol) prior to the dental treatment as compared to the post-treatment phase. GDD children who showed less favorable behavior during dental care had higher levels of sAA and salivary cortisol than GDD children with more favorable behavior, but only the sAA results were significant. In conclusion, GDD children show hyperactivity of the SNS-axis in anticipation of dental treatment which indicates the need for strategies to reduce their anxiety levels before and during dental care.Copyright © 2011 Elsevier Ltd. All rights reserved.

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