• Harefuah · Nov 1997

    Comparative Study Clinical Trial Controlled Clinical Trial

    [Analgesia in breast surgery with interpleural bupivacaine].

    • Z Crystal and Y Katz.
    • Dept. of Anesthesiology, HaEmek Medical Center, Afula.
    • Harefuah. 1997 Nov 16;133(10):430-2, 503.

    AbstractA control group of 15 patients undergoing breast surgery was given general anesthesia. In 15 other patients an interpleural block with 0.4 ml/kg bupivacaine, 0.5%, was performed 20 minutes before induction of general anesthesia for pre-emptive analgesia. This was extended further by continuous administration of bupivacaine 0.25%, 0.125 ml/kg/hr by automatic infusion pump, with supplements of opiates for postoperative pain management. The combined technique was associated with significantly reduced perioperative opiate requirement with better emergence from anesthesia, fewer side effects, a prolonged pain-free period, and overall better quality of postoperative recovery.

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