• Burns · May 2009

    Randomized Controlled Trial

    Haemostatic effects of adrenaline-lidocaine subcutaneous infiltration at donor sites.

    • P Gacto, F Miralles, J J Pereyra, A Perez, and E Martínez.
    • Department of Plastic and Reconstructive Surgery, Virgen del Rocío University Hospitals, Sevilla, Spain. purigacto@gmail.com
    • Burns. 2009 May 1;35(3):343-7.

    AbstractThis study sought methods in burn surgery to reduce postoperative pain and blood loss at donor sites. A prospective, randomised, controlled, blinded trial included 56 people undergoing burn surgery, divided into two groups. Both groups received subcutaneous infiltration at donor sites, with either 1:500,000 adrenaline solution containing added lidocaine or with 0.45% normal saline (controls). Outcome measurements included amount of intraoperative bleeding, need for electrocautery, days the hydrocolloid dressing remained on donor sites, percentage of re-epithelialised skin at donor sites 1 week after surgery and viability of skin grafts. Results indicated that subcutaneous adrenaline-lidocaine infiltration at donor sites reduced intraoperative bleeding, decreased postoperative pain, shortened the duration of surgery and general anaesthesia and accelerated re-epithelialisation at the donor site. The overall graft take in both groups was similar.

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