• Internal medicine journal · Aug 2023

    Proton pump inhibitors and the risk of acquiring a penicillin allergy label.

    • Sarah Al-Obaydi, Catherine A Popadiuk, and Taha Al-Shaikhly.
    • Department of Medicine, Penn State College of Medicine, Pennsylvania State University, Hershey, Pennsylvania, USA.
    • Intern Med J. 2023 Aug 1; 53 (8): 148114841481-1484.

    AbstractThe negative consequences of having a penicillin allergy label are well established. Penicillin allergy de-labelling improves healthcare outcomes; however, less attention is paid to modifying risk factors leading to penicillin allergy development. In this propensity score-matched retrospective cohort study, we used a de-identified population-based database (TriNetX Research Network) and examined the 30-day risk of acquiring a penicillin allergy label in patients using proton pump inhibitors (PPIs). We demonstrated a higher risk of acquiring a penicillin allergy label among PPI users compared to controls.© 2023 The Authors. Internal Medicine Journal published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Physicians.

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