• Panicos A Kyriacou.
• Research Centre for Biomedical Engineering, City, University of London, London, UK. p.kyriacou@city.ac.uk.
• J Clin Monit Comput. 2023 Dec 1; 37 (6): 148114881481-1488.

PurposePulse oximeter accuracy is important for the quality and safety of patient care. Methodological errors occurring during pulse oximeter accuracy studies can confound results. One potential source of error during pulse oximeter comparison studies is optical interference due to sensor-to-sensor crosstalk. Optical crosstalk can occur whenever pulse oximeter sensors are tested in close proximity of one another, as occurs during pulse oximeter comparison studies.MethodsThis publication represents the first comprehensive review of sensor-to-sensor crosstalk and other forms of optical interference during pulse oximeter comparison studies. A review of the published literature was undertaken to elucidate the mechanism of optical crosstalk, along with other forms of optical interference, and a solution (shielding) is offered.ResultsWhen pulse oximeter sensors are placed close to each other, as occurs during comparison studies, the red and near-infrared light used can also enter an adjacent sensor and lead to error. Pulse oximeter manufacturers have designed systems to reject some forms of optical interference, such as ambient light. However, light emanating from adjacent sensors during comparison studies can cause artifact, and this can be exacerbated by sensor malposition. Proper sensor placement and use of optical shielding are the best solutions to prevent crosstalk.ConclusionsCrosstalk and other forms of optical interference can corrupt pulse oximeter readings. Proper sensor placement and use of optical shielding of sensors are crucial steps to help protect the integrity of the data. Studies to further characterize crosstalk during pulse oximeter comparison studies are needed.© 2023. The Author(s).

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