• Medicine · Sep 2023

    Meta Analysis

    Anatomical variations and abnormalities of the maxillary region and clinical implications: A systematic review and metaanalysis.

    • Juan José Valenzuela-Fuenzalida, Belén Baez-Flores, Roberto Ávila Sepúlveda, Claudia Moya Medina, Rubén Pérez, Esteban López, Juan Sanchis, Mathias Orellana Donoso, Javiera Leyton Silva, Macarena Cecilia Rodriguez, and Joe Iwanaga.
    • Departamento de Morfología, Facultad de Medicina, Universidad Andres Bello, Santiago, Chile.
    • Medicine (Baltimore). 2023 Sep 22; 102 (38): e34510e34510.

    ObjectiveThe objective of this review is to investigate and analyze the anatomical variations present in the maxillary sinus (MS), through the examination of the prevalence of these variations, as well as the corresponding prevalence of clinically significant pathologies and complications associated with them.MethodsThe search process was carried out in the following databases; MEDLINE, SCIELO, WOS, CINHAL, SCOPUS, and GOOGLE SCHOLAR, using as search terms; "Maxillary bone," "Maxillary sinus," "Paranasal sinus," "Anatomical variations," "Sinusitis" and "Clinical anatomy."ResultsA total of 26 articles and 12969 samples were included, from which 12,594 subjects had their sex recorded giving a total of 5802 males and 6792 females. The variants reported by the included were Haller cells, Concha Bullosa, Number of septa, Hypoplastic sinus, Agger Nasi, Thickening of the MS mucosa, Deviation of the nasal septum, Accessory ostium, and Onodi cells. Among the mentioned, the ones that presented the greatest number of studies (between 8 and 10 studies included) were: the Haller Cells, the Concha Bullosa, and the Number of septa, where prevalence was 0.30, 0.36, 0.39 respectively. These variations can lead to sinusitis, cause some types of tumors, or affect neighboring structures that could be compromised by this variation.ConclusionAs a result, it is certainly complex to distinguish the presence of anatomical variations from pathological abnormalities. Therefore, knowledge of the different variations and their clinical relationships could be a useful asset for clinicians dedicated to this region.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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