• Internal medicine · Feb 2019

    Case Reports

    Bisoprolol Successfully Improved the Intraventricular Pressure Gradient in a Patient with Midventricular Obstructive Hypertrophic Cardiomyopathy with an Apex Aneurysm due to Apical Myocardial Damage.

    • Ayano Tezuka, Kenjuro Higo, Yuta Nakamukae, Sanae Nishihara, Masaki Kamikawa, Chihiro Shimofuku, Kazumasa Kawazoe, and Mitsuru Ohishi.
    • Departments of Cardiovascular Medicine, Japanese Red Cross Kagoshima Hospital, Japan.
    • Intern. Med. 2019 Feb 15; 58 (4): 535539535-539.

    AbstractMidventricular obstructive hypertrophic cardiomyopathy (MVOHCM) is a rare form of hypertrophic cardiomyopathy (HCM). An 80-year-old man was administered bisoprolol and warfarin therapies as treatment for MVOHCM with an apex aneurysm due to myocardial damage and intra-aneurysmal thrombus not complicated by atrial fibrillation. The pressure gradient in the midventricle successfully improved from 53.9 to 21.8 mmHg, and the intra-aneurysmal thrombus disappeared.

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