• Dario Massari, Ilonka N de Keijzer, and Jaap Jan Vos.
• Department of Anesthesiology, University Medical Center Groningen, Groningen, The Netherlands. d.massari@umcg.nl.
• J Clin Monit Comput. 2023 Dec 1; 37 (6): 143114331431-1433.

AbstractThe Oxygen Reserve Index (ORi) is an advanced plethysmography-derived variable that may help to quantify the degree of hyperoxia in patients receiving supplemental oxygen administration. ORi is a (relative) indicator of the actual partial pressure of oxygen dissolved in arterial blood (PaO2). As such, it may help in the titration of oxygen administration or it may help to warn the clinician of a deterioration of oxygen status of the patient.In this issue of the journal, Fadel et al. provide a 'classical' clinical validation study by assessing the correlation between ORi and PaO2 in patients about to undergo open-heart surgery. Within the moderate hyperoxic range (100-200 mmHg PaO2), there is a sound correlation between ORi and PaO2. This editorial discusses the clinical implications of this validation study and elaborates on the possible role of ORi monitoring in addition to SpO2 (peripheral arterial oxygen saturation) monitoring alone.© 2023. The Author(s), under exclusive licence to Springer Nature B.V.

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