• Amirmohammad Toloui, Mohammad Kiah, Amir Ali Zarrin, Yaser Azizi, and Mahmoud Yousefifard.
• Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran.
• Eur J Trauma Emerg Surg. 2023 Dec 18.

PurposeThis systematic review aimed to summarize the literature regarding the prognostic accuracy of the emergency surgery score (ESS).MethodPubMed, Embase, Web of Science, and Scopus were comprehensively searched by May 30, 2023. Two independent researchers performed the initial screening by reviewing the titles and abstracts of the non-duplicate records and selecting the full text of articles meeting our inclusion criteria. Finally, original studies that reported the prognostic accuracy of ESS in any emergency surgeries were included. Data from the included studies were extracted into a checklist designed based on the PRISMA guidelines. The area under the curve (AUC) was used to compare the prognostic accuracy of ESS in different settings.ResultsTwenty-six studies met the inclusion criteria. ESS performed excellently in 30-day post-op mortality (AUC 0.84-0.89) and incidence of cardiac arrest (AUC 0.86-0.88) in emergency general surgeries. The AUC of ESS in overall 30-day morbidities varied from 0.72 to 0.82 in five cohort studies. In predicting the need for ICU admission, the study with the largest sample size reported the best sensitivity of ESS at 80% and the specificity at 85%. Moreover, an outstanding accuracy was observed for the prediction of 30-day sepsis/septic shock in emergency general surgeries (AUC 0.75-0.92).ConclusionDespite the acceptable prognostic accuracy of ESS in 30-day mortality, morbidities, and in-hospital ICU admission in different emergency surgeries, the high number of required variables and the high probability of missing data highlight the need for modifications to this scoring system.© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.

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