• Mara-Louise Wester, Fleur Sampon, Jules R Olsthoorn, Mohamed A Soliman-Hamad, Saskia Houterman, MaasAngela H E MAHEMDepartment of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands., Maaike M Roefs, Michael I Meesters, Joost F J Ter Woorst, and Cardiothoracic Surgery Registration Committee of the Netherlands Heart Registration.
• Department of Cardiothoracic Surgery, Catharina Hospital Eindhoven, Eindhoven, the Netherlands.
• J. Cardiothorac. Vasc. Anesth. 2024 Apr 1; 38 (4): 924930924-930.

ObjectivesThe aim of this study was to evaluate the incidence of transfusions, including red blood cells (RBC), platelets, and fresh frozen plasma (FFP) during and after coronary artery bypass grafting (CABG) in the Netherlands. Furthermore, the authors aimed to identify the impact of sex on blood product transfusion.DesignA retrospective multicenter cohort study. Data were collected from January 2013 to December 2021 from the Netherlands Heart Registration (NHR) database.SettingThe NHR receives its data from 16 heart centers in the Netherlands.ParticipantsPatients older than 18 years who underwent CABG in the Netherlands.InterventionsCoronary artery bypass grafting with extracorporeal circulation or off-pump coronary artery bypass grafting.Measurements And Main ResultsThe incidence of blood transfusion, defined as transfusions intraoperatively and during the length of the hospital admission after CABG. In addition, a differentiation was made according to the type of transfusion (packed RBC, platelets, and FFP). In the overall cohort (N = 42,388), the number of patients who received a transfusion of any type was 27.0% (n = 11,428). Women received more often RBC transfusions compared with men (45.4% v 15.6%, respectively, p < 0.001). There was a significant difference between the 2 sexes regarding platelet transfusion (women 10.0% v men 11.1%, p = 0.005) but not in FFP transfusion. Female sex was independently associated with RBC transfusion, using the multivariate logistic regression analysis.ConclusionsThe incidence of any blood transfusion was 27.0%, and was higher in women than in men. The female sex was independently associated with receiving RBC during and after CABG.Copyright © 2024 Elsevier Inc. All rights reserved.

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