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- Akanksha Mimi Malhotra, Mauricio Arias, Matthijs Backx, Jessica Gadsby, Anna Goodman, Ysobel Gourlay, Heather Milburn, Olga Lucia Moncayo-Nieto, Deirdre Shimmin, Martin Dedicoat, and Heinke Kunst.
- Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK. Electronic address: Akanksha.malhotra@nhs.net.
- Clin Med (Lond). 2024 Jan 1; 24 (1): 100016100016.
AbstractNon-tuberculous mycobacteria (NTM) infections predominantly present as pulmonary disease. Although relatively rare, 20-30 % originate from extrapulmonary sites resulting in a wide range of clinical syndromes. Immunocompromised individuals are particularly susceptible. Clinical manifestations include skin and soft-tissue infections, lymphadenitis, musculoskeletal infections and disseminated disease. Diagnosing extrapulmonary NTM is challenging, and management is complex, often involving multiple radiological and microbiological investigations, long courses of combination antibiotic regimens and may require adjuvant surgical interventions. We highlight both the importance of involving NTM experts at an early stage and the role of a multidisciplinary approach in the diagnosis and management of these infections.Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.
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