• Saurabh Kataria, Utsav Patel, Kevin Yabut, Jayshil Patel, Rajkumar Patel, Savan Patel, Jeremiah Hilkiah Wijaya, Pankti Maniyar, Yukti Karki, Moinulhaq P Makrani, Omar Viswanath, and Alan D Kaye.
• Department of Neurology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, 71103, USA. saurabh.kataria@lsuhs.edu.
• Curr Pain Headache Rep. 2024 Feb 22.

Purpose Of ReviewThis manuscript summarizes novel clinical and interventional approaches in the management of chronic, nociceptive, and neuropathic pain.Recent FindingsPain can be defined as a feeling of physical or emotional distress caused by an external stimulus. Pain can be grouped into distinct types according to characteristics including neuropathic pain, which is a pain caused by disease or lesion in the sensory nervous system; nociceptive pain, which is pain that can be sharp, aching, or throbbing and is caused by injury to bodily tissues; and chronic pain, which is long lasting or persisting beyond 6 months. With improved understanding of different signaling systems for pain in recent years, there has been an upscale of methods of analgesia to counteract these pathological processes. Novel treatment methods such as use of cannabinoids, stem cells, gene therapy, nanoparticles, monoclonal antibodies, and platelet-rich plasma have played a significant role in improved strategies for therapeutic interventions. Although many management options appear to be promising, extensive additional clinical research is warranted to determine best practice strategies in the future for clinicians.© 2024. The Author(s).

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