• Razieh Pak, Majid Mahmoud Alilou, Abass Bakhshipour Roudsari, and Fatemeh Yousefpour.
• Faculty of Education and Psychology, University of Tabriz, Tabriz, Iran. Electronic address: pak_r@tabrizu.ac.ir.
• Pain Manag Nurs. 2024 Feb 27.

BackgroundPain is a major socio-psychological problem worldwide. Chronic pain has a negative effect on areas of psychological functioning such as depression, anxiety, and perceived stress.AimThe present study investigated the mediating role of experiential avoidance in the relationship between chronic pain and pain anxiety with pain disability.MethodsParticipants were treatment-seeking patients (N = 361) at an outpatient pain clinic in Shiraz (Fars, Iran). The Multidimensional Pain Inventory (MPI), Pain Anxiety Symptom Scale (PASS-20), Pain Disability Questionnaire (PDQ), and Acceptance and Action Questionnaire-II (AAQ-II) were used to measure multidimensional pain, anxiety, pain disability, experiential avoidance, and pain severity.ResultsThe results of the correlation revealed that a significant relationship exists between multidimensional pain and pain anxiety, pain disability, and experiential avoidance. Experiential avoidance mediated the associations from multidimensional pain and pain disability significantly. Also, experiential avoidance moderated associations between pain anxiety and pain disability significantly. In general, Structural Equation Modeling (SEM) showed that experiential avoidance mediated the relationship between multidimensional pain and pain anxiety with pain disability.ConclusionIn general, the results revealed that experiential avoidance can mediate the relationship among pain, pain anxiety, and pain disability as a maladaptive regulation strategy. The results obtained from this study seem to introduce experiential avoidance as a vulnerability factor effectively.Copyright © 2024. Published by Elsevier Inc.

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