• Br J Gen Pract · Nov 2004

    Randomized Controlled Trial Comparative Study Clinical Trial

    Randomised controlled trial of pelvic floor muscle exercises and manometric biofeedback for erectile dysfunction.

    • Grace Dorey, Mark Speakman, Roger Feneley, Annette Swinkels, Christopher Dunn, and Paul Ewings.
    • The Somerset Nuffield Hospital, Taunton, UK. grace.dorey@virgin.net
    • Br J Gen Pract. 2004 Nov 1; 54 (508): 819825819-25.

    BackgroundThe pelvic floor muscles are active in normal erectile function. Therefore, it was hypothesised that weak pelvic floor muscles could be a cause of erectile dysfunction.AimsTo compare the efficacy of pelvic floor muscle exercises and manometric biofeedback with lifestyle changes for men with erectile dysfunction.Design Of StudyRandomised controlled trial.SettingThe Somerset Nuffield Hospital, Taunton, United Kingdom.MethodFifty-five men with erectile dysfunction (median age 59.2 years; range 22-78 years) were enrolled from a local urology clinic. Of these, 28 participants were randomised to an intervention group and engaged in pelvic floor exercises, as well as receiving biofeedback and suggestions for lifestyle changes. Twenty-seven controls were solely advised on lifestyle changes. Baseline, 3- and 6-month assessments were: erectile function domain of International Index of Erectile Function (IIEF), Partner's International Index of Erectile Function (PIIEF), Erectile Dysfunction-Effect on Quality of Life (ED-EQoL), anal manometry, digital anal measurements, and clinical assessment by an assessor blind to treatment allocation. After 3 months, the control group were transferred to the active arm.ResultsAt 3 months, compared with controls, men in the intervention group showed significant mean increases in the erectile function domain of the IIEF (6.74 points, P = 0.004); anal pressure (44.16 cmH(2)O, P <0.001); and digital anal grades (1.5 grades, P <0.001). All showed further improvement in these outcomes at 6 months. Similar benefits were seen in men of the control arm after transfer to active treatment. A total of 22 (40.0%) participants attained normal function, 19 (34.5%) participants had improved erectile function, and 14 (25.5%) participants failed to improve.ConclusionPelvic floor muscle exercises and biofeedback are an effective treatment for men with erectile dysfunction.

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