• Semin Respir Crit Care Med · Mar 2024

    Approach to Pulmonary Nodules in Connective Tissue Disease.

    • Brian Gaffney and David J Murphy.
    • Department of Radiology, St Vincent's University Hospital, Dublin, Ireland.
    • Semin Respir Crit Care Med. 2024 Mar 28.

    AbstractThe assessment of pulmonary nodules is a common and often challenging clinical scenario. This evaluation becomes even more complex in patients with connective tissue diseases (CTDs), as a range of disease-related factors must also be taken into account. These diseases are characterized by immune-mediated chronic inflammation, leading to tissue damage, collagen deposition, and subsequent organ dysfunction. A thorough examination of nodule features in these patients is required, incorporating anatomic and functional information, along with patient demographics, clinical factors, and disease-specific knowledge. This integrated approach is vital for effective risk stratification and precise diagnosis. This review article addresses specific CTD-related factors that should be taken into account when evaluating pulmonary nodules in this patient group.Thieme. All rights reserved.

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