• A&A practice · Apr 2024

    Case Reports

    Transient Acute Diplopia as a Rare Side Effect of Hydromorphone: A Case Report.

    • Leah J Lee, Brittani Bungart, Brian Wainger, Jonathan Gorky, Ashley So, and Jingping Wang.
    • From the Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts.
    • A A Pract. 2024 Apr 1; 18 (4): e01780e01780.

    AbstractDiplopia, or double vision, has been listed as a rare adverse effect of intravenous hydromorphone, although there are no case studies or literature documenting this. We detail a case of acute transient diplopia correlated with the use of intraoperative hydromorphone and postoperative hydromorphone patient-controlled analgesia. Although the mechanism for this adverse effect is unknown, there may be risk factors that predispose patients to the potential toxic metabolic effects of hydromorphone. We share the first published case of diplopia as a clinically relevant adverse effect of hydromorphone and propose a potential reason behind this association.Copyright © 2024 International Anesthesia Research Society.

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