• Clin Med (Lond) · Dec 2015

    Management of bile acid malabsorption using low-fat dietary interventions: a useful strategy applicable to some patients with diarrhoea-predominant irritable bowel syndrome?

    • Lorraine Watson, Amyn Lalji, Shankar Bodla, Ann Muls, H Jervoise N Andreyev, and Clare Shaw.
    • Department of Nutrition and Dietetics, The Royal Marsden NHS Foundation Trust, London, UK.
    • Clin Med (Lond). 2015 Dec 1; 15 (6): 536540536-40.

    AbstractThis study evaluates the efficacy of low-fat dietary interventions in the management of gastrointestinal (GI) symptoms due to bile acid malabsorption. In total, 40 patients with GI symptoms and a 7-day (75)selenium homocholic acid taurine (SeHCAT) scan result of <20%, were prospectively recruited and then advised regarding a low-fat dietary intervention. Before and after dietary intervention, patients rated their GI symptoms using a 10-point numerical scale, and recorded their intake in 7-day dietary diaries. After dietary intervention, the median scores for all GI symptoms decreased, with a significant reduction for urgency, bloating, lack of control, bowel frequency (p ≥: 0.01). Mean dietary fat intake reduced to 42 g fat after intervention (p ≥: 0.01). Low-fat dietary interventions in patients with a SeHCAT scan result of <20% leads to clinically important improvement in GI symptoms and should be widely used.© Royal College of Physicians 2015. All rights reserved.

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