• J Cardiothorac Surg · Jan 2010

    Relative adrenal insufficiency and hemodynamic status in cardiopulmonary bypass surgery patients. A prospective cohort study.

    • José L Iribarren, Juan J Jiménez, Domingo Hernández, Lisset Lorenzo, Maitane Brouard, Antonio Milena, María L Mora, and Rafael Martínez.
    • Critical Care Department, Hospital Universitario de Canarias, Ofra s/n, La Cuesta, 38320 La Laguna, Tenerife, España. joseluis.iribarren@gmail.com
    • J Cardiothorac Surg. 2010 Jan 1;5:26.

    BackgroundThe objectives of this study were to determine the risk factors for relative adrenal insufficiency in cardiopulmonary bypass patients and the impact on postoperative vasopressor requirements.MethodsProspective cohort study on cardiopulmonary bypass patients who received etomidate or not during anesthetic induction. Relative adrenal insufficiency was defined as a rise in serum cortisol Results120 elective cardiopulmonary bypass patients were included. Relative adrenal insufficiency (Deltacortisol ConclusionsRelative adrenal insufficiency in elective cardiopulmonary bypass patients may induce postoperative vasopressor dependency. Use of etomidate in these patients is a modifiable risk factor for the development of relative adrenal insufficiency that should be avoided.

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