• Medicina · Jan 2024

    Case Reports

    [Malignant melanotic nerve sheath tumor of the posterior mediastinum].

    • Agustín Buero, Soledad B Olivera Lopez, Ariel Tchercansky, Leonardo G Pankl, Domingo J Chimondeguy, Mayra Samudio, Julián Mendez, and Gustavo A Lyons.
    • Servicio de Cirugía Torácica, Hospital Británico de Buenos Aires, Buenos Aires, Argentina. E-mail: a_buero@hotmail.com.
    • Medicina (B Aires). 2024 Jan 1; 84 (2): 324328324-328.

    AbstractMelanotic schwannoma (MS) is a rare and infrequent subtype of schwannoma characterized by cytoplasmic deposits of melanosomes (melanin). Unlike the other schwannomas, it could have malignant transformation. Due to distinctive characteristics and atypical behavior from classic schwannomas subtypes, MS were renamed and reclassified as "melanocytic malignant neural sheath tumor" in the 5th ed. of the World Health Organization's classification of central nervous system tumors in 2021. We present two cases of MS that underwent complete surgical resection.

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