• Am. J. Med. · May 2024

    Review

    Coronary Microvascular Dysfunction: A Guide for Clinicians.

    • Hannah Smati, Frank W Sellke, Jamieson M Bourque, Yusuf Kamran Qadeer, Giampaolo Niccoli, Rocco A Montone, and Chayakrit Krittanawong.
    • Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
    • Am. J. Med. 2024 May 7.

    AbstractDysfunction of the coronary microvasculature has become increasingly recognized as an important mechanism of myocardial ischemia in patients without obstructive coronary artery disease. The causes and management of coronary microvascular dysfunction remain poorly understood and is still largely based on extrapolation of epicardial coronary artery disease data. Quantification of myocardial blood flow and flow reserve have improved diagnosis, though important questions remain In this review, we explain current understanding of the spectrum of pathophysiology of coronary microvascular dysfunction, summarize current diagnostic techniques to assess for coronary microvascular dysfunction, and appraise the limited data on management options specifically for patients with coronary microvascular dysfunction.Copyright © 2024. Published by Elsevier Inc.

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