• J Res Med Sci · Jan 2024

    Seroepidemiology of Toxoplasma gondii in diabetic patients type 2 by enzyme-linked immunosorbent assay method in Zabol City, 2017-2018.

    • Mansour Dabirzadeh, Mojtaba Sargazi, and Somayeh Bagheri.
    • Department of Parasitology and Mycology, Faculty of Medicine, Zabol University of Medical Sciences, Zabol, Iran.
    • J Res Med Sci. 2024 Jan 1; 29: 1919.

    BackgroundType 2 diabetes mellitus (T2DM) is prone to opportunistic infections, including toxoplasmosis, due to an immunodeficiency system. This study aimed to evaluate the serum of people with T2DM to determine the titer of anti-toxoplasma antibodies in patients and compare it with the control group.Materials And Methods720 blood samples have been carried out between October and the end of January 2017 in Sistan, and Baluchestan provinces in southeastern Iran, of these, 360 samples were related to healthy individuals (control), and 360 samples were related to T2DM individuals. The immunoglobulin (Ig) M and IgG enzyme-linked immunosorbent assay methods have been used to detect toxoplasmosis. The data were analyzed using SPSS-19, Chi-square, and Fisher's exact test to compare statistical parameters.ResultsIn this cross-sectional study, out of 360 samples of T2DM by ELISA method, 60% samples in diabetic patients and 48.1% in control group were IgG positive (P < 0.05). Nearly 2.5% samples in diabetic patients and 0.3% in control group were IgM positive (P < 0.05).ConclusionAnti-toxoplasma antibodies including IgG and IgM were higher in diabetic patient in comparison to control group.Copyright: © 2024 Journal of Research in Medical Sciences.

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