• Br J Anaesth · Nov 1988

    Randomized Controlled Trial Clinical Trial

    Use of the post-tetanic count to monitor recovery from intense neuromuscular blockade in children.

    • C L Gwinnutt and G Meakin.
    • Department of Anaesthesia, Royal Manchester Children's Hospital, Pendlebury.
    • Br J Anaesth. 1988 Nov 1;61(5):547-50.

    AbstractThe post-tetanic count was investigated as a method of monitoring intense neuromuscular blockade in children. One of five myoneural blockers (atracurium, vecuronium, pancuronium, tubocurarine or alcuronium) was given to groups of six children during nitrous oxide-oxygen-halothane anaesthesia. During recovery, the first post-tetanic response always preceded the first train-of-four response. The interval between the appearance of the first post-tetanic response and the first train-of-four response was typically 5-10 min for the intermediate-acting agents vecuronium and atracurium, and 20-30 min for the long-acting agents pancuronium, alcuronium and tubocurarine. A post-tetanic count of 6 with alcuronium and tubocurarine, or 7 with vecuronium, atracurium and pancuronium indicated that recovery of the first train-of-four response was imminent.

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