• Med. J. Aust. · Sep 2000

    Case Reports

    Three fatal pneumococcal polysaccharide vaccine failures.

    • J N Hanna, D J Wenck, and D N Murphy.
    • Tropical Public Health Unit, Queensland Health, Cairns. jeffery_hanna@health.qld.gov.au
    • Med. J. Aust. 2000 Sep 18; 173 (6): 305307305-7.

    AbstractThree Indigenous Australian adults died of invasive pneumococcal disease, despite vaccination with the pneumococcal polysaccharide vaccine an average of 18 months previously. Pneumococcal isolates from the patients had serotypes that are included in the vaccine. Two of the adults were alcoholics and the other had heavy recent alcohol intake. The public health implications, and possible optimal vaccination schedules to minimise vaccine failures, are discussed.

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