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- R Rodriguez-Roisin.
- Department of Medicine, University of Barcelona, Barcelona, Spain. roisin@medicina.ub.es
- Chest. 2000 May 1; 117 (5 Suppl 2): 398S401S398S-401S.
AbstractIn patients with COPD, an acute worsening of respiratory symptoms is often described as an exacerbation. Exacerbations are associated with a significant increase in mortality, hospitalization, and health-care utilization, but there is currently no widely accepted definition of what constitutes an exacerbation of COPD. This paper summarizes the discussions of the workshop, "COPD: Working Towards a Greater Understanding," in which the participants proposed the following working definition of an exacerbation of COPD: a sustained worsening of the patient's condition, from the stable state and beyond normal day-to-day variations, that is acute in onset and necessitates a change in regular medication in a patient with underlying COPD.
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