• Wei Feng, Xiaoxiao Xiong, Qile Wang, Siying Chen, Yao Ma, and Dongming Zhu.
• Wei Feng Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province 215006, P.R. China. Department of Hepatobiliary and Pancreatic Surgery, Nanjing Drum Tower Hospital Group Suqian Hospital, Suqian, Jiangsu Province 223800, P.R. China.
• Pak J Med Sci. 2025 Jan 1; 41 (1): 119124119-124.

ObjectiveTo analyze the efficacy of indocyanine green fluorescence (ICG-F)-assisted laparoscopic hepatectomy in patients with hepatocellular carcinoma (HCC).MethodsThis retrospective study included 120 patients with HCC who underwent laparoscopic hepatectomy in The First Affiliated Hospital of Soochow University from February 2020 to November 2022. Among them, 58 patients underwent conventional laparoscopic surgery (laparoscopic group), and 62 patients underwent ICG-F assisted laparoscopic surgery (ICG-F group). The perioperative conditions, levels of inflammatory factors before and after the operation, levels of liver function indexes, and incidence of complications in the two groups were statistically analyzed.ResultsThe perioperative indexes of patients in the ICG-F group improved compared to the laparoscopic group (P<0.05). On the second day after the operation, the inflammatory response in the two groups was significantly higher than before the operation and significantly lower in the ICG-F group compared to the laparoscopic group (P<0.05). Liver function of the two groups decreased two days after the surgery and was markedly lower in the ICG-F group than the laparoscopic group (P<0.05). The incidence of complications in the ICG-F group was significantly lower than that in the laparoscopic group (P<0.05).ConclusionsCompared with conventional laparoscopic surgery, ICG-F-assisted laparoscopic hepatectomy for HCC can reduce surgical injury, alleviate the degree of inflammatory response, protect patients' liver function, and significantly reduce the risk of complications.Copyright: © Pakistan Journal of Medical Sciences.

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