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- Pantelis Lioumis, Dubravko Kicić, Petri Savolainen, Jyrki P Mäkelä, and Seppo Kähkönen.
- HUSLAB, Hospital District of Helsinki and Uusimaa, Finland. plioumis@cc.hut.fi
- Hum Brain Mapp. 2009 Apr 1;30(4):1387-96.
AbstractNavigated transcranial magnetic stimulation combined with electroencephalography (nTMS-EEG), allows noninvasive studies of cortical excitability and connectivity in humans. We investigated the reproducibility of nTMS-EEG in seven healthy subjects by repeating left motor and prefrontal cortical stimulation with a 1-week interval. TMS was applied at three intensities: 90, 100, and 110% of subjects' motor threshold (MT). The TMS-compatible neuronavigation system guaranteed precise repositioning of the stimulation coil. The responses were recorded by a 60-channel whole head TMS-compatible EEG amplifier. A high overall reproducibility (r > 0.80) was evident in nTMS-EEG responses over both hemispheres for both motor and prefrontal cortical stimulation. The results suggest that nTMS-EEG is a reliable tool for studies investigating cortical excitability changes in the test-retest designs.2008 Wiley-Liss, Inc.
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