• Aust N Z J Psychiatry · Aug 1998

    Case Reports

    Mania associated with codeine and paracetamol.

    • K G Orr, J Mostert, and D J Castle.
    • Armadale Clinic, Perth, Australia.
    • Aust N Z J Psychiatry. 1998 Aug 1;32(4):586-8.

    ObjectiveWe describe a patient in whom a manic episode was precipitated by use of panadeine forte, a preparation containing codeine and paracetamol.Clinical PictureThe patient developed a discrete manic psychotic episode.TreatmentThe treatment consisted of cessation of the Panadeine forte and antipsychotic medication.OutcomeThe patient made a complete recovery after 1 week.ConclusionsMania can be induced by large doses of Panadeine forte, particularly if there is a biological predisposition.

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