• Crit Care · Jan 2011

    Comment

    Cardiovascular consequences of cooling in critical care.

    • Paul Steendijk.
    • Department of Cardiology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands. p.steendijk@lumc.nl
    • Crit Care. 2011 Jan 1;15(1):119.

    AbstractThis commentary discusses a paper by Filseth and colleagues in a previous issue of Critical Care. The authors describe the cardiovascular effects of induced hypothermia, focusing particularly on post-hypothermic ventricular function. The findings indicate that the treatment resulted in reduced systolic but unchanged diastolic left ventricular function with compensatory effects on heart rate and systemic vascular resistance. The novel aspects of this study are the registration of ventricular function using sophisticated, load-independent indices in a clinically relevant, large animal model during the entire cooling and re-warming trajectory of hypothermia therapy.

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